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Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling
Heptahelical G protein-coupled receptors are the most diverse and therapeutically important family of receptors in the human genome. Ligand binding activates heterotrimeric G proteins that transmit intracellular signals by regulating effector enzymes or ion channels. G protein signaling is terminate...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879915/ https://ncbi.nlm.nih.gov/pubmed/20427692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.109.002436 |
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