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Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling

Heptahelical G protein-coupled receptors are the most diverse and therapeutically important family of receptors in the human genome. Ligand binding activates heterotrimeric G proteins that transmit intracellular signals by regulating effector enzymes or ion channels. G protein signaling is terminate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Luttrell, Louis M., Gesty-Palmer, Diane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879915/
https://ncbi.nlm.nih.gov/pubmed/20427692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.109.002436
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