PDE3, but not PDE4, reduces β(1)- and β(2)-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients

Eitemau Tebyg

• Differential regulation of β(2)-adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle
  gan: Afzal, Faraz, et al.
  Cyhoeddwyd: (2011)
• Phosphodiesterase-4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (−)-adrenaline mediated through mouse cardiac β(1)-adrenoceptors
  gan: Galindo-Tovar, A, et al.
  Cyhoeddwyd: (2007)
• Human atrial β(1L)-adrenoceptor but not β(3)-adrenoceptor activation increases force and Ca(2+) current at physiological temperature
  gan: Christ, Torsten, et al.
  Cyhoeddwyd: (2011)
• Inotropy and L-type Ca(2+) current, activated by β(1)- and β(2)-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart
  gan: Christ, Torsten, et al.
  Cyhoeddwyd: (2009)
• Positive inotropic and lusitropic effects mediated via the low-affinity state of β(1)-adrenoceptors in pithed rats
  gan: Zakrzeska, Agnieszka, et al.
  Cyhoeddwyd: (2005)