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Positive inotropic and lusitropic effects mediated via the low-affinity state of β(1)-adrenoceptors in pithed rats

1. Activation by CGP 12177 and cyanopindolol of the human and rat low-affinity state of β(1)-adrenoceptors increases frequency and contractile force and hastens relaxation in isolated cardiac tissues, and probably relaxes isolated vessels. In order to identify the positive inotropic, positive lusitr...

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Autori principali: Zakrzeska, Agnieszka, Schlicker, Eberhard, Kwolek, Grzegorz, Kozłowska, Hanna, Malinowska, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751196/
https://ncbi.nlm.nih.gov/pubmed/16151438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706382
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