Atypical cardiostimulant β-adrenoceptor in the rat heart: stereoselective antagonism by bupranolol but lack of effect by some bupranolol analogues

1. Atypical β-adrenoceptors resistant to propranolol, but blocked by bupranolol, increase contractile force and/or frequency of the heart in humans and rats. We compared the potencies of the enantiomers of bupranolol and examined the possible effects of seven bupranolol analogues including bevantolo...

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Detalhes bibliográficos
Main Authors: Malinowska, Barbara, Kieć-Kononowicz, Katarzyna, Flau, Karsten, Godlewski, Grzegorz, Kozłowska, Hanna, Kathmann, Markus, Schlicker, Eberhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573984/
https://ncbi.nlm.nih.gov/pubmed/12922943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705390
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