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Human atrial β(1L)-adrenoceptor but not β(3)-adrenoceptor activation increases force and Ca(2+) current at physiological temperature

BACKGROUND AND PURPOSE: It has been proposed that BRL37344, SR58611 and CGP12177 activate β(3)-adrenoceptors in human atrium to increase contractility and L-type Ca(2+) current (I(Ca-L)). β(3)-adrenoceptor agonists are potentially beneficial for the treatment of a variety of diseases but concomitant...

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Bibliografske podrobnosti
Main Authors: Christ, Torsten, Molenaar, Peter, Klenowski, Paul M, Ravens, Ursula, Kaumann, Alberto J
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042194/
https://ncbi.nlm.nih.gov/pubmed/20726983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00996.x
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