Putative β(4)-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca(2+): comparison with atrial receptors and relationship to (−)-[(3)H]-CGP 12177 binding

1. We identified putative β(4)-adrenoceptors by radioligand binding, measured increases in ventricular contractile force by (−)-CGP 12177 and (±)-cyanopindolol and demonstrated increased Ca(2+) transients by (−)-CGP 12177 in rat cardiomyocytes. 2. (−)-[(3)H]-CGP 12177 labelled 13–22 fmol mg(−1) prot...

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Detaylı Bibliyografya
Asıl Yazarlar: Sarsero, Doreen, Molenaar, Peter, Kaumann, Alberto J, Freestone, Nicholas S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571781/
https://ncbi.nlm.nih.gov/pubmed/10602323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702936
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