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Stimulation of cyclic AMP-dependent protein kinase in rat atria by (–;)-CGP 12177 through an atypical β-adrenoceptor

Mammalian hearts possess an atypical β-adrenoceptor (non-β(1), non-β(2), non-β(3)) through which (–)-4-(3-t-butylamino-2-hydroxypropoxy)benzimidazol-2-one ((–)-CGP 12177) causes cardiostimulant effects. Here we showed that (–)-CGP 12177 increased the activity of adenosine 3′ : 5′-cyclic monophosphat...

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Detalhes bibliográficos
Main Authors: Kaumann, Alberto J, Lynham, James A
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564608/
https://ncbi.nlm.nih.gov/pubmed/9105691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701053
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