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α(1)-Adrenoceptor antagonist properties of CGP 12177A and other β-adrenoceptor ligands: evidence against β(3)- or atypical β-adrenoceptors in rat aorta

1. The α(1)-adrenoceptor antagonist properties of the β-adrenoceptor nonconventional partial agonist, CGP 12177A, was investigated in functional assays in rat aorta and in radioligand binding assays in rat cerebral cortical membranes. In addition, binding affinities of other β-adrenoceptor ligands w...

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Main Authors: Brahmadevara, Nataraj, Shaw, Angus M, MacDonald, Allan
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575050/
https://ncbi.nlm.nih.gov/pubmed/15205310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705840
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