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The β(3)‐adrenoceptor agonist mirabegron increases human atrial force through β(1)‐adrenoceptors: an indirect mechanism?

BACKGROUND AND PURPOSE: Mirabegron has been classified as a β(3)‐adrenoceptor agonist approved for overactive bladder syndrome. We investigated possible cardiac effects of mirabegron in the absence or presence of β‐adrenoceptor subtype antagonists. In view of its phenylethanolamine structure, we inv...

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Bibliografski detalji
Izdano u:Br J Pharmacol
Glavni autori: Mo, Weilan, Michel, Martin C, Lee, Xiang Wen, Kaumann, Alberto J, Molenaar, Peter
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522995/
https://ncbi.nlm.nih.gov/pubmed/28574581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13897
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