The preferential β(3)-adrenoceptor agonist BRL 37344 increases force via β(1)-/β(2)-adrenoceptors and induces endothelial nitric oxide synthase via β(3)-adrenoceptors in human atrial myocardium

1. The present study investigated the effects of the preferential β(3)-AR agonist BRL 37344 (BRL) on force of contraction (FOC), Ca(2+)-transient and eNOS-activity in human right atrial myocardium. 2. BRL concentration-dependently caused an increase in FOC that was paralleled by an increase in Ca(2+...

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Detalhes bibliográficos
Main Authors: Pott, C, Brixius, K, Bundkirchen, A, Bölck, B, Bloch, W, Steinritz, D, Mehlhorn, U, Schwinger, R H G
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573689/
https://ncbi.nlm.nih.gov/pubmed/12569077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705065
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