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Metabolic responses to BRL37344 and clenbuterol in soleus muscle and C2C12 cells via different atypical pharmacologies and β(2)-adrenoceptor mechanisms

BACKGROUND AND PURPOSE: Picomolar concentrations of the β(3)-adrenoceptor agonist BRL37344 stimulate 2-deoxyglucose uptake in soleus muscle via undefined receptors. Higher concentrations alter uptake, apparently via β(2)-adrenoceptors. Effects of BRL37344 and β(2)-adrenoceptor agonists are compared....

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Detalhes bibliográficos
Main Authors: Ngala, R A, O'Dowd, J, Wang, S J, Agarwal, A, Stocker, C, Cawthorne, M A, Arch, J R S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567876/
https://ncbi.nlm.nih.gov/pubmed/18552870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.244
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