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The preferential β(3)-adrenoceptor agonist BRL 37344 increases force via β(1)-/β(2)-adrenoceptors and induces endothelial nitric oxide synthase via β(3)-adrenoceptors in human atrial myocardium
1. The present study investigated the effects of the preferential β(3)-AR agonist BRL 37344 (BRL) on force of contraction (FOC), Ca(2+)-transient and eNOS-activity in human right atrial myocardium. 2. BRL concentration-dependently caused an increase in FOC that was paralleled by an increase in Ca(2+...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573689/ https://ncbi.nlm.nih.gov/pubmed/12569077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705065 |
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