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The β(3)‐adrenoceptor agonist mirabegron increases human atrial force through β(1)‐adrenoceptors: an indirect mechanism?

BACKGROUND AND PURPOSE: Mirabegron has been classified as a β(3)‐adrenoceptor agonist approved for overactive bladder syndrome. We investigated possible cardiac effects of mirabegron in the absence or presence of β‐adrenoceptor subtype antagonists. In view of its phenylethanolamine structure, we inv...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Main Authors: Mo, Weilan, Michel, Martin C, Lee, Xiang Wen, Kaumann, Alberto J, Molenaar, Peter
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522995/
https://ncbi.nlm.nih.gov/pubmed/28574581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13897
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