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The β(3)‐adrenoceptor agonist mirabegron increases human atrial force through β(1)‐adrenoceptors: an indirect mechanism?

BACKGROUND AND PURPOSE: Mirabegron has been classified as a β(3)‐adrenoceptor agonist approved for overactive bladder syndrome. We investigated possible cardiac effects of mirabegron in the absence or presence of β‐adrenoceptor subtype antagonists. In view of its phenylethanolamine structure, we inv...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Mo, Weilan, Michel, Martin C, Lee, Xiang Wen, Kaumann, Alberto J, Molenaar, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522995/
https://ncbi.nlm.nih.gov/pubmed/28574581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13897
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