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The Hbs1-Dom34 Protein Complex Functions in Non-stop mRNA Decay in Mammalian Cells

In yeast, aberrant mRNAs lacking in-frame termination codons are recognized and degraded by the non-stop decay (NSD) pathway. The recognition of non-stop mRNAs involves a member of the eRF3 family of GTP-binding proteins, Ski7. Ski7 is thought to bind the ribosome stalled at the 3′-end of the mRNA p...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Saito, Syuhei, Hosoda, Nao, Hoshino, Shin-ichi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
RNA
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682582/
https://ncbi.nlm.nih.gov/pubmed/23667253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.448977
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