Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway

The 2′-5′-oligoadenylate synthetase (OAS)/RNase L pathway is an innate immune system that protects hosts against pathogenic viruses and bacteria through cleavage of exogenous single-stranded RNA; however, this system's selective targeting mechanism remains unclear. Here, we identified an mRNA q...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Nogimori, Takuto, Nishiura, Kyutatsu, Kawashima, Sho, Nagai, Takahiro, Oishi, Yuka, Hosoda, Nao, Imataka, Hiroaki, Kitamura, Yoshiaki, Kitade, Yukio, Hoshino, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326797/
https://ncbi.nlm.nih.gov/pubmed/30395302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1087
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