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Inhibition of the OAS/RNase L pathway by viruses

The OAS/RNase L system was one of the first characterized interferon effector pathways. It relies on the synthesis, by oligoadenylate synthetases (OAS), of short oligonucleotides that act as second messengers to activate the latent cellular RNase L. Viruses have developed diverse strategies to escap...

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Detalhes bibliográficos
Publicado no:Curr Opin Virol
Main Authors: Drappier, Melissa, Michiels, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185432/
https://ncbi.nlm.nih.gov/pubmed/26231767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2015.07.002
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