A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L

The OAS/RNase L pathway is one of the best-characterized effector pathways of the IFN antiviral response. It inhibits the replication of many viruses and ultimately promotes apoptosis of infected cells, contributing to the control of virus spread. However, viruses have evolved a range of escape stra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Drappier, Melissa, Jha, Babal Kant, Stone, Sasha, Elliott, Ruth, Zhang, Rong, Vertommen, Didier, Weiss, Susan R., Silverman, Robert H., Michiels, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927464/
https://ncbi.nlm.nih.gov/pubmed/29652922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006989
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados