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108: Preventing activation of the IFN inducible OAS-RNase L pathway by A-kinase anchoring protein 7 (AKAP7)
The 2′,5′-oligoadenylate (2-5A) synthetase (OAS)-RNase L system is an interferon inducible pathway that blocks virus infections by cleaving viral and cellular single-stranded RNA. Viral dsRNA, produced during infections by both RNA and DNA viruses, activates OAS (a pathogen recognition receptor) res...
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| Udgivet i: | Cytokine |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Published by Elsevier Ltd.
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7128459/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2013.06.111 |
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