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Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop off to initiate no-go decay

No-go decay (NGD) is one of several mRNA surveillance systems dedicated to the removal of defective mRNAs from the available pool. Two interacting factors, Dom34 and Hbs1, are genetically implicated in NGD in yeast. Here we show, using a reconstituted yeast translation system, that Dom34:Hbs1 intera...

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Hlavní autoři: Shoemaker, Christopher J., Eyler, Daniel E., Green, Rachel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022135/
https://ncbi.nlm.nih.gov/pubmed/20947765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1192430
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