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Analysis of Dom34 and Its Function in No-Go Decay

Eukaryotic mRNAs are subject to quality control mechanisms that degrade defective mRNAs. In yeast, mRNAs with stalls in translation elongation are targeted for endonucleolytic cleavage by No-Go decay (NGD). The cleavage triggered by No-Go decay is dependent on Dom34p and Hbs1p, and Dom34 has been pr...

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Detalhes bibliográficos
Main Authors: Passos, Dario O., Doma, Meenakshi K., Shoemaker, Christopher J., Muhlrad, Denise, Green, Rachel, Weissman, Jonathan, Hollien, Julie, Parker, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704154/
https://ncbi.nlm.nih.gov/pubmed/19420139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0028
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