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Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop off to initiate no-go decay

No-go decay (NGD) is one of several mRNA surveillance systems dedicated to the removal of defective mRNAs from the available pool. Two interacting factors, Dom34 and Hbs1, are genetically implicated in NGD in yeast. Here we show, using a reconstituted yeast translation system, that Dom34:Hbs1 intera...

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Detalhes bibliográficos
Main Authors: Shoemaker, Christopher J., Eyler, Daniel E., Green, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022135/
https://ncbi.nlm.nih.gov/pubmed/20947765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1192430
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