Ubiquitin-dependent recruitment of the Bloom Syndrome helicase upon replication stress is required to suppress homologous recombination

Limiting the levels of homologous recombination (HR) that occur at sites of DNA damage is a major role of BLM helicase. However, very little is known about the mechanisms dictating its relocalization to these sites. Here, we demonstrate that the ubiquitin/SUMO-dependent DNA damage response (UbS-DDR)...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Tikoo, Shweta, Madhavan, Vinoth, Hussain, Mansoor, Miller, Edward S, Arora, Prateek, Zlatanou, Anastasia, Modi, Priyanka, Townsend, Kelly, Stewart, Grant S, Sengupta, Sagar
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680739/
https://ncbi.nlm.nih.gov/pubmed/23708797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.117
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars