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BLM helicase stimulates the ATPase and chromatin-remodeling activities of RAD54
Mutation of BLM helicase results in the autosomal recessive disorder Bloom syndrome (BS). Patients with BS exhibit hyper-recombination and are prone to almost all forms of cancer. BLM can exhibit its anti-recombinogenic function either by dissolution of double Holliday junctions or by disruption of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729260/ https://ncbi.nlm.nih.gov/pubmed/19671661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.051813 |
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