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BLM helicase stimulates the ATPase and chromatin-remodeling activities of RAD54

Mutation of BLM helicase results in the autosomal recessive disorder Bloom syndrome (BS). Patients with BS exhibit hyper-recombination and are prone to almost all forms of cancer. BLM can exhibit its anti-recombinogenic function either by dissolution of double Holliday junctions or by disruption of...

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Autors principals: Srivastava, Vivek, Modi, Priyanka, Tripathi, Vivek, Mudgal, Richa, De, Siddharth, Sengupta, Sagar
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729260/
https://ncbi.nlm.nih.gov/pubmed/19671661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.051813
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