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p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway

There is growing evidence that the p53 tumour suppressor downregulates vascular endothelial growth factor (VEGF) expression, although the underlying mechanisms remain unclear and controversial. Here we provide insights from in vitro experiments and in vivo xenotransplantation assays that highlight a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Farhang Ghahremani, M, Goossens, S, Nittner, D, Bisteau, X, Bartunkova, S, Zwolinska, A, Hulpiau, P, Haigh, K, Haenebalcke, L, Drogat, B, Jochemsen, A, Roger, P P, Marine, J-C, Haigh, J J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679451/
https://ncbi.nlm.nih.gov/pubmed/23449391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.12
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