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p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway
There is growing evidence that the p53 tumour suppressor downregulates vascular endothelial growth factor (VEGF) expression, although the underlying mechanisms remain unclear and controversial. Here we provide insights from in vitro experiments and in vivo xenotransplantation assays that highlight a...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679451/ https://ncbi.nlm.nih.gov/pubmed/23449391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.12 |
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