p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway

There is growing evidence that the p53 tumour suppressor downregulates vascular endothelial growth factor (VEGF) expression, although the underlying mechanisms remain unclear and controversial. Here we provide insights from in vitro experiments and in vivo xenotransplantation assays that highlight a...

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Detalhes bibliográficos
Main Authors: Farhang Ghahremani, M, Goossens, S, Nittner, D, Bisteau, X, Bartunkova, S, Zwolinska, A, Hulpiau, P, Haigh, K, Haenebalcke, L, Drogat, B, Jochemsen, A, Roger, P P, Marine, J-C, Haigh, J J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679451/
https://ncbi.nlm.nih.gov/pubmed/23449391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.12
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