p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway

There is growing evidence that the p53 tumour suppressor downregulates vascular endothelial growth factor (VEGF) expression, although the underlying mechanisms remain unclear and controversial. Here we provide insights from in vitro experiments and in vivo xenotransplantation assays that highlight a...

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Autori principali: Farhang Ghahremani, M, Goossens, S, Nittner, D, Bisteau, X, Bartunkova, S, Zwolinska, A, Hulpiau, P, Haigh, K, Haenebalcke, L, Drogat, B, Jochemsen, A, Roger, P P, Marine, J-C, Haigh, J J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679451/
https://ncbi.nlm.nih.gov/pubmed/23449391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.12
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