p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway

There is growing evidence that the p53 tumour suppressor downregulates vascular endothelial growth factor (VEGF) expression, although the underlying mechanisms remain unclear and controversial. Here we provide insights from in vitro experiments and in vivo xenotransplantation assays that highlight a...

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Bibliografske podrobnosti
Main Authors: Farhang Ghahremani, M, Goossens, S, Nittner, D, Bisteau, X, Bartunkova, S, Zwolinska, A, Hulpiau, P, Haigh, K, Haenebalcke, L, Drogat, B, Jochemsen, A, Roger, P P, Marine, J-C, Haigh, J J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679451/
https://ncbi.nlm.nih.gov/pubmed/23449391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.12
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