Rb is required for retinal angiogenesis and lamination

Retinoblastoma tumor suppressor (Rb) promotes cell cycle exit, survival, differentiation, and tumor suppression in the retina. Here, we show it is also essential for vascularization and lamination. Despite minimal effects on Hif1a target expression, intraretinal vascular plexi did not form in the Rb...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Zhou, Yi, Wei, Ran, Zhang, Liu, Chen, Yongjiang, Lu, Suying, Liang, Chen, Wang, Yujiao, Xiao, Lirong, Zhang, Junjun, Bremner, Rod, Chen, Danian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840357/
https://ncbi.nlm.nih.gov/pubmed/29511172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0411-6
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