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DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice
Retinitis pigmentosa (RP) is a group of inherited retinal degenerative diseases causing progressive loss of photoreceptors. Numerous gene mutations are identified to be related with RP, but epigenetic modifications may also be involved in the pathogenesis. Previous studies suggested that both DNA me...
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Publicado no: | Cell Death Dis |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833420/ https://ncbi.nlm.nih.gov/pubmed/29472543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0349-8 |
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