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Design, Synthesis and Biological Activity of Multifunctional α,β- Unsaturated Carbonyl Scaffolds for Alzheimer’s Disease
A series of compounds containing an α,β-unsaturated carbonyl moiety, such as chalcones and coumarins were designed, synthesized and tested in a variety of assays to assess their potential as anti-Alzheimers’ disease (AD) agents. The investigations included the inhibition of cholinesterases (AChE, Bu...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676911/ https://ncbi.nlm.nih.gov/pubmed/23540646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.02.103 |
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