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Disassembly of preformed amyloid beta fibrils by small organofluorine molecules

A potential therapeutic approach for Alzheimer’s disease is to reduce the amount of toxic amyloid-beta oligomers and fibrillar amyloid plaques. In order to contribute to this approach the ability of small organofluorine compounds that were previously reported as successful inhibitors of fibrillogene...

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Detalhes bibliográficos
Main Authors: Sood, Abha, Abid, Mohammed, Sauer, Catharine, Hailemichael, Samson, Foster, Michelle, Török, Béla, Török, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056901/
https://ncbi.nlm.nih.gov/pubmed/21354796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.02.012
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