Structure-activity relationship of organofluorine inhibitors of amyloid-beta self-assembly

A broad group of structurally diverse small organofluorine inhibitors have been synthesized and evaluated in the self-assembly of amyloid β. The major goal was to generate a diverse library of compounds with the same functional group and observe general structural features that characterize the olig...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Török, Béla, Sood, Abha, Bag, Seema, Kulkarni, Aditya, Borkin, Dmitry, Lawler, Elizabeth, Dasgupta, Sujaya, Landge, Shainaz, Abid, Mohammed, Zhou, Weihong, Foster, Michelle, LeVine, Harry, Török, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848461/
https://ncbi.nlm.nih.gov/pubmed/22351619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100569
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