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Diaryl Hydrazones as Multifunctional Inhibitors of Amyloid Self-Assembly(†)

The design and application of an effective, new class of multifunctional small molecule inhibitors of amyloid self-assembly are described. Several compounds, based on the diaryl hydrazone scaffold were designed. Forty-four substituted derivatives of this core structure were synthesized using a varie...

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Detalhes bibliográficos
Main Authors: Török, Béla, Sood, Abha, Bag, Seema, Tulsan, Rekha, Ghosh, Sanjukta, Borkin, Dmitry, Kennedy, Arleen R., Melanson, Michelle, Madden, Richard, Zhou, Weihong, LeVine, Harry, Török, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608202/
https://ncbi.nlm.nih.gov/pubmed/23346953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3012059
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