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Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer’s disease agents

The design, synthesis and assessment of β-carboline core-based compounds as potential multifunctional agents against several processes that are believed to play a significant role in Alzheimer’s disease (AD) pathology, are described. The activity of the compounds was determined in Aβ self-assembly (...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Horton, William, Sood, Abha, Peerannawar, Swarada, Kugyela, Nandor, Kulkarni, Aditya, Tulsan, Rekha, Tran, Chris D., Soule, Jessica, LeVine, Harry, Török, Béla, Török, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282889/
https://ncbi.nlm.nih.gov/pubmed/27923619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.11.067
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