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Substrate-modulated Cytochrome P450 17A1 and Cytochrome b(5) Interactions Revealed by NMR
The membrane heme protein cytochrome b(5) (b(5)) can enhance, inhibit, or have no effect on cytochrome P450 (P450) catalysis, depending on the specific P450, substrate, and reaction conditions, but the structural basis remains unclear. Here the interactions between the soluble domain of microsomal b...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675632/ https://ncbi.nlm.nih.gov/pubmed/23620596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468926 |
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