טוען...
Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression
Thymic involution during aging is a major cause of decreased production of T cells and reduced immunity. Here we show that inactivation of Rb family genes in young mice prevents thymic involution and results in an enlarged thymus competent for increased production of naive T cells. This phenotype or...
שמור ב:
| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674705/ https://ncbi.nlm.nih.gov/pubmed/23669396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121716 |
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