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Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution

Thymus function requires extensive cross-talk between developing T-cells and the thymic epithelium, which consists of cortical and medullary TEC. The transcription factor FOXN1 is the master regulator of TEC differentiation and function, and declining Foxn1 expression with age results in stereotypic...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:	PLoS One
المؤلفون الرئيسيون:	O’Neill, Kathy E., Bredenkamp, Nicholas, Tischner, Christin, Vaidya, Harsh J., Stenhouse, Frances H., Peddie, C. Diana, Nowell, Craig S., Gaskell, Terri, Blackburn, C. Clare
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Public Library of Science 2016
الموضوعات:	Research Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4794177/ https://ncbi.nlm.nih.gov/pubmed/26983083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151666
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Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution

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