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Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution

Thymus function requires extensive cross-talk between developing T-cells and the thymic epithelium, which consists of cortical and medullary TEC. The transcription factor FOXN1 is the master regulator of TEC differentiation and function, and declining Foxn1 expression with age results in stereotypic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: O’Neill, Kathy E., Bredenkamp, Nicholas, Tischner, Christin, Vaidya, Harsh J., Stenhouse, Frances H., Peddie, C. Diana, Nowell, Craig S., Gaskell, Terri, Blackburn, C. Clare
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794177/
https://ncbi.nlm.nih.gov/pubmed/26983083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151666
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