Cell-Autonomous Defects in Thymic Epithelial Cells Disrupt Endothelial-Perivascular Cell Interactions in the Mouse Thymus

The thymus is composed of multiple stromal elements comprising specialized stromal microenvironments responsible for the development of self-tolerant and self-restricted T cells. Here, we investigated the ontogeny and maturation of the thymic vasculature. We show that endothelial cells initially ent...

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Autors principals: Bryson, Jerrod L., Griffith, Ann V., Hughes III, Bernard, Saito, Fumi, Takahama, Yousuke, Richie, Ellen R., Manley, Nancy R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672159/
https://ncbi.nlm.nih.gov/pubmed/23750244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065196
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