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Thymic stromal cells: roles in atrophy and age-associated dysfunction of the thymus
Atrophy of the thymus, the primary site of T lymphocyte generation, is a hallmark of the aging immune system. Age-associated thymic atrophy results in diminished output of new, naïve T cells, with immune sequelae that include diminished responses to novel pathogenic challenge and vaccines, as well a...
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| Veröffentlicht in: | Exp Gerontol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869099/ https://ncbi.nlm.nih.gov/pubmed/29278750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.12.022 |
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