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Thymic stromal cells: roles in atrophy and age-associated dysfunction of the thymus

Atrophy of the thymus, the primary site of T lymphocyte generation, is a hallmark of the aging immune system. Age-associated thymic atrophy results in diminished output of new, naïve T cells, with immune sequelae that include diminished responses to novel pathogenic challenge and vaccines, as well a...

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Publicat a:Exp Gerontol
Autors principals: Cepeda, Sergio, Griffith, Ann V.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869099/
https://ncbi.nlm.nih.gov/pubmed/29278750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.12.022
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