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Dynamic changes in epithelial cell morphology control thymic organ size during atrophy and regeneration

T lymphocytes must be produced throughout life, yet the thymus, where T lymphocytes are made, exhibits accelerated atrophy with age. Even in advanced atrophy, however, the thymus remains plastic, and can be regenerated by appropriate stimuli. Logically, thymic atrophy is thought to reflect senescent...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Venables, Thomas, Griffith, Ann V., DeAraujo, Alice, Petrie, Howard T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765001/
https://ncbi.nlm.nih.gov/pubmed/31562306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11879-2
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