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Dynamic changes in epithelial cell morphology control thymic organ size during atrophy and regeneration

T lymphocytes must be produced throughout life, yet the thymus, where T lymphocytes are made, exhibits accelerated atrophy with age. Even in advanced atrophy, however, the thymus remains plastic, and can be regenerated by appropriate stimuli. Logically, thymic atrophy is thought to reflect senescent...

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Publicado en:Nat Commun
Autores principales: Venables, Thomas, Griffith, Ann V., DeAraujo, Alice, Petrie, Howard T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765001/
https://ncbi.nlm.nih.gov/pubmed/31562306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11879-2
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