Lopinavir/Ritonavir Pharmacokinetics in HIV/HCV-Coinfected Patients With or Without Cirrhosis

Liver disease may alter the pharmacokinetics of antiretrovirals and produce changes in plasma protein binding. The aim was to evaluate the pharmacokinetics of total and unbound lopinavir (LPV) in HIV-infected patients with and without hepatitis C virus (HCV) coinfection. Fifty-six HIV+ patients rece...

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Main Authors: Micheli, Valeria, Regazzi, Mario, Dickinson, Laura, Meraviglia, Paola, Villani, Paola, Khoo, Saye H., Viganò, Paolo, Cordier, Laura, Cusato, Maria, Duca, Piergiorgio, Orlando, Giovanna, Rizzardini, Giuliano, Back, David J., Cargnel, Antonietta
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672992/
https://ncbi.nlm.nih.gov/pubmed/18520602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e318177209e
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