Sequential Population Pharmacokinetic Modeling of Lopinavir and Ritonavir in Healthy Volunteers and Assessment of Different Dosing Strategies

Nonlinear mixed-effects modeling was applied to explore the relationship between lopinavir and ritonavir concentrations over 72 h following drug cessation and also to assess other lopinavir and ritonavir dosing strategies compared to the standard 400-mg–100-mg twice-daily dose. Data from 16 healthy...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dickinson, Laura, Boffito, Marta, Back, David, Else, Laura, von Hentig, Nils, Davies, Geraint, Khoo, Saye, Pozniak, Anton, Moyle, Graeme, Aarons, Leon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2011
Aiheet:
Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101471/
https://ncbi.nlm.nih.gov/pubmed/21422211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00887-10
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia