Population pharmacokinetics of ritonavir-boosted atazanavir in HIV-infected patients and healthy volunteers

OBJECTIVES: The aim of this study was to develop and validate a population pharmacokinetic model to: (i) describe ritonavir-boosted atazanavir concentrations (300/100 mg once daily) and identify important covariates; and (ii) evaluate the predictive performance of the model for lower, unlicensed ata...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dickinson, Laura, Boffito, Marta, Back, David, Waters, Laura, Else, Laura, Davies, Geraint, Khoo, Saye, Pozniak, Anton, Aarons, Leon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680345/
https://ncbi.nlm.nih.gov/pubmed/19329800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp102
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