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Pharmacokinetic analysis to assess forgiveness of boosted saquinavir regimens for missed or late dosing
OBJECTIVES: One potential concern of once-daily protease inhibitor administration is low trough concentrations and ultimately the ‘forgiveness’ or robustness in comparison with the originally licensed twice-daily dose. To give an estimation of ‘forgiveness’, we determined the length of time plasma d...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672987/ https://ncbi.nlm.nih.gov/pubmed/18467305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkn187 |
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