Lopinavir/ritonavir population pharmacokinetics in neonates and infants

AIMS: Because of immature hepatic metabolism, lopinavir could present specific pharmacokinetics in the first weeks of life. We aimed at determining the optimal dosing regimen in neonates and infants weighing 1 to 10.5 kg. METHODS: Lopinavir/ritonavir (LPV/r) pharmacokinetics were studied in 96 infan...

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Main Authors: Urien, Saik, Firtion, Ghislaine, Anderson, Suzanne T, Hirt, Deborah, Solas, Caroline, Peytavin, Gilles, Faye, Albert, Thuret, Isabelle, Leprevost, Marthe, Giraud, Carole, Lyall, Hermione, Khoo, Saye, Blanche, Stéphane, Tréluyer, Jean-Marc
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2011
Teme:
Short Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099384/
https://ncbi.nlm.nih.gov/pubmed/21564164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.03926.x
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