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Impact of body weight and missed doses on lopinavir concentrations with standard and increased lopinavir/ritonavir doses during late pregnancy

OBJECTIVES: To assess the influence of body weight and missed doses on lopinavir pharmacokinetics with standard and increased doses of lopinavir/ritonavir melt extrusion tablets during late pregnancy. PATIENTS AND METHODS: Lopinavir concentration data during the third trimester of pregnancy were poo...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Cressey, Tim R., Urien, Saik, Capparelli, Edmund V., Best, Brookie M., Buranabanjasatean, Sudanee, Limtrakul, Aram, Rawangban, Boonsong, Sabsanong, Prapan, Treluyer, Jean-Marc, Jourdain, Gonzague, Stek, Alice, Lallemant, Marc, Mirochnick, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267507/
https://ncbi.nlm.nih.gov/pubmed/25261418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku367
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