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Age-Related Effects on Nelfinavir and M8 Pharmacokinetics: a Population Study with 182 Children

As a relationship between nelfinavir antiretroviral efficacy and plasma concentrations has been previously established, nelfinavir pharmacokinetics was investigated in order to optimize the individual treatment schedule in a pediatric population. A population pharmacokinetic model was developed to d...

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Hlavní autoři: Hirt, Déborah, Urien, Saïk, Jullien, Vincent, Firtion, Ghislaine, Rey, Elisabeth, Pons, Gérard, Blanche, Stéphane, Treluyer, Jean-Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426418/
https://ncbi.nlm.nih.gov/pubmed/16495250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.910-916.2006
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